The Faculty of Chemistry and Technology in Split was officially opened on October 22nd, 1960. The growth of the chemical industry in the Split region was the main incentive for its establishment. It was a part of the University of Zagreb until 1974, when the University of Split was founded. In the first two years lessons were held at the Bishop's Palace building while laboratory exercises were held in the premises of the Pedagogical Academy and the Medical School. The Faculty moved to the new address (Nikola Tesla Street 10) in 1962 while laboratory exercises for most of the subjects moved to Kaštel Sućurac. Finally, the Faculty and all its activities moved to the new building at the UNIST campus in 2016, at the address Ruđera Boškovića 35.

University study Chemical Technology has been organized and conducted from the very beginning. Professional study program Chemical Technology has also been conducted since 1977/78. Over the years, these study programs have been constantly changing and upgrading according to the needs of the region and its economy, respecting the principles of sustainable development as well as the European and world trends in science and higher education. Until 2003, the university study lasted for nine semesters and was carried out through three orientations: Chemical Technology Processes (since the beginning of the Faculty), Environmental Protection (since 1982/83) and Chemistry and Technology of Mediterranean Cultures (since 2001/2002). Professional study Chemical Technology lasted for five semesters and was conducted through two orientations: Process Technology and Food Technology.

Programs according to the Bologna Approach were established in 2003: undergraduate (3 years), graduate (2 years) and postgraduate doctoral studies (3 years). In addition to the existing undergraduate study Chemical Technology (orientation Chemical Engineering) since 2005/06 undergraduate study Chemistry has also being conducted. The undergraduate study Chemical Technology, orientation Environmental Protection was introduced in academic year 2012/2013, while undergraduate study Food Technology was introduced in academic year 2015/2016.

At the graduate studies, the following orientations were offered: Materials and Environmental Protection and Mediterranean Cultures (for graduate study Chemical Technology) and Organic Chemistry and Biochemistry and Environmental Chemistry (for graduate study Chemistry). In 2017/18 the graduate study Food Technology was introduced while orientation Mediterranean Culture was suspended. Until academic year 2015/16 a professional study of Chemical Technology with orientations Chemical Technology and Materials and Food Technology has been conducted. In 2015/16 they were replaced by undergraduate professional study Protection and Recovery of Materials.

The Faculty continuously conducts and organizes postgraduate studies in the field of chemistry and chemical engineering. The first postgraduate studies Engineering Chemistry (1972/73) and Engineering Chemistry - Chemistry and Technology of Macromolcules (1978/79) were organized within the University of Zagreb. Postgraduate studies in Chemical engineering and Chemistry have been organized within the University of Split since 1983/84. In 2008/09 the new postgraduate doctoral study Chemical Engineering in Materials Development and Environmental Protection was established and in 2012/13 the new postdoctoral study Chemistry of the Mediterranean Environment was established.

The Faculty of Chemistry and Technology and the Faculty of Medicine set up an integrated undergraduate and graduate study program Pharmacy in 2011/12.

Faculty of Chemistry and Technology has a very rich scientific activity. Faculty teachers are involved in numerous scientific projects as the main researchers, associates or consultants of their specialty. Their quality is proven by constantly publishing scientific papers in domestic and international journals and by participating in domestic and international scientific conferences. They are also active in the organization of scientific and professional conferences, as the members of numerous scientific and professional domestic and international associations and societies, reviewers of scientific projects and journals etc.

From its foundation until today, the Faculty has been paying special attention to the cooperation with the Dalmatian economy, taking into account the role of science in the industry. Further development of the Faculty is focused on continuous improvement of teaching and scientific work. In this context, the organization of the Faculty adapts to the demands of a new era in which the reconstruction of chemical and related industries, changes in market relations and the transformation into the market economy of the European model are taking place. Large chemical giants in our region have ceased to exist, and there is a growing tendency to develop small and medium-sized plants for the production of special materials and products subject to complex environmental conditions. Through the modernization of curricula and scientific research, the Faculty of Chemistry and Technology aims to meet the challenges of time, contribute to the general good and to the development of our society.